1. Melee/Hunters DPS the casters Cult Adherent (99% resist to magic DPS)
2. Casters DPS the melee adds Cult Fanatic (99% resist to physical DPS)
3. Between adds, DPS her shield down
4. After the shields down, if you have a ghost targeting you, get out of the raid, or you'll blow everyone up.
5. Phase 2 tanks swap Lady Deathwhisper every 2-3 stacks of Touch of Inisignificance

*Notes: As always, stay out of stuff on the floor, the floor is evil & everything that spawns on it is evil as well.